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Allisartan Isoproxil

CAS No. 947331-05-7

Allisartan Isoproxil( —— )

Catalog No. M27845 CAS No. 947331-05-7

Allisartan Isoproxil, an angiotensin II receptor antagonist, is used to treat mild to moderate essential hypertension.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 264 Get Quote
5MG 403 Get Quote
10MG 592 Get Quote
25MG 888 Get Quote
50MG 1242 Get Quote
100MG 1701 Get Quote
500MG 3402 Get Quote
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Biological Information

  • Product Name
    Allisartan Isoproxil
  • Note
    Research use only, not for human use.
  • Brief Description
    Allisartan Isoproxil, an angiotensin II receptor antagonist, is used to treat mild to moderate essential hypertension.
  • Description
    Allisartan Isoproxil, an angiotensin II receptor antagonist, is used to treat mild to moderate essential hypertension.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Femal and male Sprague-Dawley ratsDosage:20, 80 and 320 mg/kg Administration:Result:Decreased body-weight gain at 320 mg/kg/day in both sexes as well as at the 80-mg/kg/day dose in females. Decreased erythrocyte parameters in males, and decreased heart weight and exacerbation of chronic progressive nephropathy (CPN) severity in males at 80 and 320 mg/kg/day.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Furin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    947331-05-7
  • Formula Weight
    553.02
  • Molecular Formula
    C27H29ClN6O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (180.83 mM)
  • SMILES
    CCCCc1nc(Cl)c(C(=O)OCOC(=O)OC(C)C)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lisa E J Douglas, et al. A highly selective, cell-permeable furin inhibitor BOS-318 rescues key features of cystic fibrosis airway disease. Cell Chem Biol. 2022 Jun 16;29(6):947-957.e8.
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